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Xeljanz vs Humira for Rheumatoid Arthritis Treatment

Rheumatoid arthritis is an autoimmune inflammatory condition that affects the joints of the body, causing swelling and pain. While the condition mostly affects adults over the age of 55, it can also occur in younger adults. For those who suffer from rheumatoid arthritis, treatment options may include immunosuppressive drugs such as Xeljanz and Humira. So how do Xeljanz and Humira compare in terms of effectiveness and side effects?

Xeljanz (Tofacitinib) is a newer drug on the market that was approved by the FDA in 2012. It is a Janus Kinase (JAK) inhibitor and works by blocking certain molecules that cause inflammation, thus helping to reduce the pain and swelling associated with rheumatoid arthritis. Studies have shown that Xeljanz can be more effective than standard treatments, such as methotrexate, and provides rapid relief from symptoms.

Humira (Adalimumab) is a biologic drug that was approved by the FDA in 2002. It modifies the immune system and helps to reduce inflammation associated with rheumatoid arthritis. It also helps slow down the progression of the disease and can be used in combination with other medications for better results.

Studies have shown that both Xeljanz and Humira can effectively control rheumatoid arthritis, but Xeljanz can provide relief from symptom faster. One study showed that 67 percent of patients taking Xeljanz achieved at least a 20 percent reduction in pain and swelling within three months, compared to 53 percent of patients taking Humira.

When it comes to side effects, both drugs can cause serious infections, an increased risk of certain cancers, and an elevated risk of stroke or heart attack. Xeljanz is associated with an increased risk of serious blood clots, while Humira can raise the risk of lymphoma.

Overall, Xeljanz and Humira are both effective treatments for rheumatoid arthritis, but they may not be suitable for everyone. It's important to discuss all the benefits and risks with your doctor so the best treatment plan can be determined.

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